9 Best Hypochlorous-Acid Sprays Tested 2026, Vetted by Dermatologists

After struggling with acne since she was 12, actress Lili Reinhart sought to create a skincare brand that was super acne-safe and effective at targeting and preventing breakouts. That’s how Personal Day was born. This hypochlorous acid spray from the brand is great for sensitive, acne-prone skin because it’s alcohol-free, non-comedogenic, and only contains three ingredients: water, sodium chloride, and hypochlorous acid.

Best for Eczema-Prone Skin: Loma Lux Eczemol OTC Topical Eczema Spray

• Pros: Neutral scent
• Cons: Heavy spray

This multitasking mist doesn’t just soothe—it works four ways: fighting bacteria, calming inflammation, relieving itch, and boosting blood flow for faster healing. It’s been rigorously tested to be safe and non-irritating, with no sting or weird reactions. “It’s one of my go-to hypochlorous acid sprays, thanks to its easy-to-use, non-irritating formula,” says Dr. King.

The National Eczema Association officially approves it, so if you have reactive skin, you’re in good hands. “The formula is straight to the point—exactly what you want in a hypochlorous spray,” Lee says. “The topical skin spray is more of a true spray than a fine mist, so distance is key. Personally, I found that rather than directly applying to my face, I like to spritz this one into the air and walk through it—just like I would with perfume.”

Best for Piercings: Aquia Hypochlorous Acid Spray for Face and Skin

Aquia Hypochlorous Acid Spray for Face and Skin

• Pros: Multi-tasking and reduces irritation
• Cons: Smelly

Along with treating issues like acne, eczema, blepharitis, and even chalazion (a bump on the eyelid), this multi-tasking spray is a favorite for pierced ears, too. Containing 0.015% hypochlorous acid, this formula is beloved for its simplicity, ease of use, and relatively affordable price.

“I’ve actually used this on my own kids after they got their ears pierced,” says Geeta Yadav, MD, a board-certified dermatologist and founder of FACET Dermatology. “It’s designed for wound care and aftercare, which fits really well with what hypochlorous acid does: it helps keep the area clean and supports healing without being harsh or stinging.” For anyone with a fresh piercing or irritated skin where the barrier is compromised, this type of product can be a nice, gentle option. Dr. Yadav also likes that the bottle has a more controlled spray, so you can apply it exactly where you need it.

Best for Dry Skin: Velež HOCL Hydrating Face Mist

Velež HOCL Hydrating Face Mist

• Pros: Less risk of dryness or irritation
• Cons: Without sodium as a stabilizer, the formula may break down faster and become less effective over time

Whether your skin is feeling dull and dehydrated, irritated and inflamed, or just plain over it, Velež HOCL Hydrating Face Mist speeds up recovery and rejuvenation. “This offers a fine mist that feels ultra-soothing—especially after an in-office derm procedure [like a chemical peel],” says Dr. Kobets. “The lightweight application makes it comfortable to spritz throughout the day, even over makeup.” Unlike other hypochlorous sprays, this one is completely sodium-free, which means it delivers all the skin-calming benefits of hypochlorous acid without any chance of irritation or dryness.

Best for Body Odor: Base Laboratories Hypochlorous Acid Spray for Face & Skin

Base Laboratories Hypochlorous Acid Spray for Face & Skin

• Pros: Can spray product at any angle
• Cons: Some have reported breakouts after use