Woman’s hands can triple in size amid rare swelling attacks

Eighteen months ago, Ms Davies’ consultant – who specialises in HAE – suggested trialling a new medication at Southmead Hospital.

It involves an injection into the subcutaneous fat under the skin to deliver a drug into the bloodstream.

The drug works to lower the amount of a protein produced by the liver that causes the swelling.

Ms Davies was given the real drug, rather than a placebo.

She noticed an “immediate” difference and has only experienced one flare-up since starting the treatment.

“It’s amazing – it’s changed my life,” she said.

“It’s helped provide a space to do what I want without worrying.

“I feel genuinely very cared for and the research team at North Bristol NHS Trust has been really great.”

She added: “It’s changed my opinion of doing a trial.”